Low-dose metformin targets the lysosomal AMPK pathway through PEN2

Low-dose metformin targets the lysosomal AMPK path via PEN2

The molecular target of the antidiabetic medication metformin is recognized as PEN2, a subunit of γ-secretases, as well as the PEN2– ATP6AP1 axis uses possible targets for evaluating for metformin substitutes.Read More …